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Dushyant Patel Aim of The Present Work

S.K.P.C.P.E.R., Kherva 17 M .Pharm. Thesis

CHAPTER 3: AIM OF THE PRESENT WORK

3.1 AIM OF THE PRESENT WORK:

¾ Nowadays it is important to estimate drug concentration in biological fluid to achieve

better therapeutic effect and to check out content of drug in pharmaceutical dosage

forms.

¾ Many methods are available to estimate GBP in human plasma, but our aim behind this

project is to develop accurate, precise and validated method for estimation of GBP which

has higher selectivity and specificity, accuracy and precision which can give reliable

results without interference from biological matrix.

¾ Also no single extractive spectrophotometric method is available to estimate GBP in

pharmaceutical dosage forms.

The specific aim of the research work was

 To develop and validate LC-MS/MS method for estimation of GBP in human plasma.

 To develop and validate spectrophotometric method for determination of GBP in

pharmaceutical dosage forms.

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